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Doctors' Answers to "Frequently Asked Questions" - Arthrotec

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An indi vidual patient is always advised to consult their own physician.

[posted 01/15/2000]
Question: I have been given Arthrotec 50 mg to treat a ruptured disc in my lower back. I take both diovan and norvasc for hypertension, and the Arthrotec info sheet says I should not take Arthotec with an ace inhibitor. Info on diovan is confusing -- is it an ace inhibitor or not? Should I take Arthrotec with these drugs? Where can I get more info? The doctor who prescribed Arthrotec indicated there was no problem. Thanks.

Answer: Diovan is a angiotensin receptor blocker. There is a caution in the PDR about it's potential to decrease renal blood flow in the presence of ACE inhibitors. However, clinically, I have never seen this and it is a reversable problem with stopping the Arthrotec. Although diovan is a different class of drug, it would probably have similar risks in occasional patients. But, watch your blood pressure while taking it. Any of the non-steroidals can increase sodium retention and raise your blood pressure(a differnt problem than referred to above).

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