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Doctors' Answers to "Frequently Asked Questions" - Bacitracin

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

Polymixin B and Bacitracin
Question:Is polymixin B and Bacitracin stable in an irrigation solution. Also, is there any drug interaction between the two?

Answer:Polymixin is an antifungal agent used mainly in topical creams and ointments. It was found being produced by Bacillus polymyxa and is used clinically against gram negative organisms and some fungal elements. It is occasionally used in bowel regiments since it is not absorbed into the body and occasionally for systemic infections. Bacitracin was found being produced by Bacillus subtilis and is also an antibacterial agent. These agents have no side effects or interactions when used in external or topical ointments and are combined in several products sold by prescription.
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