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Doctors' Answers to "Frequently Asked Questions" - Divalproex

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

Divalproex - side effects/kidney function [posted 1/8/99]
Question: I am seeking information regarding the use and side effects of divalproex and its relationship to kidney function.

Answer: Depakote(divalproex sodium) is an anti-seizure drug. It has been used in the treatment of chronic pain syndromes and migraine headaches. Side effects center on liver dysfunction and alterations in white blood cells. Headache, nausea, drowsiness, tremor, and a flu like syndrome are also common. Renal problems are uncommon, but reported.

Divalproex [posted 8/11/98]
Question: Are there any side effects of zopiclone (zimovane) and clomipramine, both on their own and together, and would that result in abnormal thinking? I have heard of a syndrome called "serotonin syndrome". Would that be possible in this case, with the two being taken together?

Answer: Sorry, never heard of this one.

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