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Doctors' Answers to "Frequently Asked Questions" - Megestrol

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

General Information
Question: Please advise drug information on Megestrol and any risk factors.

Answer: Megestrol is the generic name for Megace. This is a synthetic derivation of progesterone. It is commonly given to patients to stimulate appetite and put on weight. I have used in many patients with wasting syndromes ranging from AIDs to different cancers. Occasionally with elderly people who are losing weight. Like progesterone it can cause fluid retention, nausea, diarrhea. It also can cause a rash and impotence.

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