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Doctors' Answers to "Frequently Asked Questions" - Moban

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

Moban [posted 7/21/98]
Question: I am a special education teacher at a public high school. One of my students w/TS, OCD, ADHD, CD and/or ODD has recently been taking Moban and experiencing a good result. Well, he hasn't pulled a knife on anyone for over a week and hasn't stolen anything for almost as long. He is very restless and distractible, but he is cooperative and feeling hopeful for the first time in the 4 years I've known him. Can you steer me toward any information about this medication's off label use for conduct disorder in teens?

Answer: I'd check with the manufacturer concerning published data in this area. That would be Gate Pharmaceuticals 800-292-4283, they're usually glad to send you any information you would need/want.

Question: Please tell me about Moban suspension. A family member is taking it (10 mg, two times a day). She has been on it for about 4 weeks, and we see no change in her. She is 89 years old and has been in a nursing home for about 2 months. Will this help her depression?

Answer: Moban(molindone hydrochloride) is a tranquilizing drug-- not an antidepressant. Typically, tranquilizing drugs will result in some amount of depression. This varies by the drug and the patient. Moban is usually classified as a major tranquilizer and used to suppress psychotic disorders. If your family member also has depression this will probably not be affected by this drug. This drug can cause an unusual condition called tardive dyskinesia which is involuntary smacking and rolling of the lips and facial muscles. Once this occurs it is not reversible. Drowsiness is the major side effect in most patients. Some become rigid and Parkinsonian like, and there are reports of nausea, fast heart beats etc.

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