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Doctors’ Answers to “Frequently Asked Questions” – Kawasaki Disease

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

Kawasaki Disease

Question: Can you tell me anything about Kawasaki Disease? Will using aspirin have any side effects?

Answer: Kawasaki Disease is an inflammatory disease of medium and large arteries that leads to fibrosis and stenosis of the arteries. The cause is not clear, but is supposed to be a non-specific inflammatory response. Curiously, it is more common in patients with skin test positive TB. Treatment during the acute phase is usually steroids with focus on anti-inflammatories in the chronic stage. Aspirin is used to avoid further damage or clots in the narrowed, fibrosed arteries. Curiously, Kawasaki Disease seems to be somewhat more prevalent in Japan, and Korea.