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Frequently Asked Questions

Doctors’ Answers to “Frequently Asked Questions” – Helicobacter Pylori

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

[posted 01/28/2000]

Question: i recently had a miscarrage after 3 months being pregnant. I found out 2 months later that i have the helocobactor pyloric in my stomach. i am back on fertility treatments. will the H. Pylori hurt the baby if i get pregnant again? I am not taking any meds except Serophen for infertility.

Answer: The treament of H. pylori is generally antibiotics plus bismuth solutions. Some of the antibiotics could have an effect, but there should be no residual after you stop them(usually one to two weeks of treatment). Same with the bismuth compounds(pepto bismo and the like). Prilosec/prevacid is the other treatment and some mds will continue this drug. I need some more specifics about what your treatment options will be.

[posted 11/27/1999]

Question: To treat the HP I was given the following regimen

Pepto Bismol 1 oz 4x a day for two weeks

Tetracycline 500mg 4x a day for two weeks

Metronidazole 250mg 1 tablet 4x a day STARTING 4 days

AFTER you have been on tetracycline.

This morning I started the regimen by taking the one oz PeptoBismol

I then made a mistake and took the metronidazol INSTEAD of the tetracycline BY MISTAKE. What should I do know. Im concerned I screwed up the drug therapy because there must have been a reason to start the metronizadol 4 days after the tetracycline. Should I wait a few days and start all over????

Answer: This should be ok. There are probably 50 different regiments for treating H. pylori infections. There are so many because we don’t have one regimen that is 100% effective. Most are 70-90% effective. So, even if you follow everything by the letter, you have a 10-20% chance of reoccurance. Many regimens use the tetracycline and metronidazole together. Just go back to the basic regiment today and don’t worry about it.

[posted 11/21/1999]

Question: I’m taking the triple therapy to eradicate H. Pylori. You mention

including Pepto Bismol. How much and how often? Also, I

read on your site that H. Pylori is passed from person to

person. Are there measures I can/should take to avoid passing this

to anyone?

Answer: No one knows exactly the mode of transmission. We assume person to person transfer since it occurs in clusters but the exact mode of transmission is unclear. Most physicians recommend a tablespoon 3 or 4 times a day on an empty stomach. I wouldn’t worry about the infectious part, too little is currently known.

Helicobacter Pylori

Question: What is the best treatment for this?

Answer: This topic is currently under debate. However, it appears that a combination of either Prilosec or

Prevacid with 2 antibiotics (usually Erythromycin plus Flagyl-or equivalent) plus Pepto Bismol for

ten days or so.

Helicobacter Pylori

Question: I would like to know how H. Pylori is transmitted. Is it the cause of some ulcers or does it thrive on ulcerated G.I. tissue.

Answer: Helicobacter Pylori is a spiral shaped organism found exclusively in gastric lining tissue. If there

has been a change in the normal lining of the small intestine that is immediately after the

stomach (the “duodenum”), to that seen in the stomach, the H. Pylori can also reside there. It is

found in 10% of all healthy people under the age of 30, and 60% of healthy people over the age

of 60. Although the specifics and exact route is still unconfirmed, it is likely that H. Pylori is

spread by direct person to person contact. Although H. Pylori is the cause of at least one form

of erosive gastritis (stomach lining inflammation), and it seen in 90% of patients with ulcer

disease (stomach/duodenum), most people infected with H. Pylori do not develop any of these

problems. The organism survives in the normal mucous covering of our stomach lining, and

does not need disease tissue to live. Eradication of newly discovered H. Pylori in a patient, with

a combination of antibiotics, and special antacids reduces the risk of recurrent ulcers, and helps

to heal ones that are being treated at the time. If you are concerned about ulcer disease, or H.

Pylori, speak to your physician. They can provide you with up to date information about the

disorder, its symptoms, and treatment.