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Doctors’ Answers to “Frequently Asked Questions” – Ibuprofen

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

Ibuprofen [posted 8/13/98]

Question: Could you tell me about dermatologic side effects of ibuprofen – types, frequency and risk of cross-reactions with other NSAIDs.

Answer: There aren’t any major ones except rare rash, what were you interested in?

Allergic Reaction to Profen LA (Ibuprofen)

Question: Is there a web page where I can gain access to drug

“pull-sheets”?

I have a relative who is having what appears to be an allergic

reaction to Profen LA. These appear in the form of shingle-like

reactions. Is there any documentation of these type of reactions,

or are you aware if this is a possible reaction?

Answer: By drug “pull sheets” do you mean drug inserts? Usually the manufacturer of the individual

drug you are seeking has these. Use your search engine and the drug company name. They are also

available at your pharmacist on request.

I am not familiar with this specific reaction. Try contacting McNeil at 215-233-7000.

Erythema Multiforme and Ibuprofen/Aspirin

Question: Ibuprofen and Aspirin both have a probable causal relationship

with Erythema Multiforme (EM). If both were included in a pain killer

would this increase the likelihood of triggering EM to any great extent?

Answer: These two medications would not be included in the same medication due to overlapping

effectiveness and overlapping side effects. The potential side effects (like EM) would be

multiplied, hence, these two would not be used concurrently.

Ibuprofen

Question: I am taking 2 regular strength Ibuprofen tablets almost every day. Am I running a risk of damaging my kidneys or stomach lining?

Answer: Long term regular use of any analgesic will cause renal damage. This usually needs 10 years at high doses or 20 years at moderate doses.